Effect of halothane on calcium transport in isolated hepatic endoplasmic reticulum.
نویسندگان
چکیده
The effects of halothane on calcium transport by microtomes prepared from rat liver have been studied. Pre-incubation of microsomal suspensions in the presence of halothane, irreversibly inactivated ATPdependent calcium transport. The effects were doie-dependent and time-dependent and were potentiated by acid conditions (pH 6.0). The observed in vitro effects of halothane may, by increasing cytosolic concentrations of calcium, be relevant to the hepatotozic effects of halothane.
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عنوان ژورنال:
- British journal of anaesthesia
دوره 54 9 شماره
صفحات -
تاریخ انتشار 1982